Anti-CD276

Anti-CD276
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030044.100 100 µl - -

3 - 19 business days*

477.00€
 
Costimulatory B7 molecules (e.g., B7-1, or CD80, MIM 112203) signal through CD28 (MIM 186760)... more
Product information "Anti-CD276"
Costimulatory B7 molecules (e.g., B7-1, or CD80, MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. Applications: Western Bloting: 1:500-1:2000., Immunofluorescence: 1:200-1:1000., Flow cytometry: 1:200-1:400., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-B7H3, Anti-B7-H3, Anti-CD276, Anti-PSEC0249, Anti-4Ig-B7-H3, Anti-B7 homolog 3, Anti-CD276 antigen, Anti-Costimulatory molecule
Supplier: United States Biological
Supplier-Nr: 030044

Properties

Application: ELISA, FC, WB
Antibody Type: Monoclonal
Clone: 13B122
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human CD276 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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