Anti-CD274 / PD-L1, clone SQab1716

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG65862.50	50 µl		-	-	6 - 14 business days*		460.00€

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Protein function: Plays a critical role in induction and maintenance of immune tolerance to self... more

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Product information "Anti-CD274 / PD-L1, clone SQab1716"

Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443, PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin- 10 (IL10) (PubMed:10581077). [The UniProt Consortium]

Keywords:	Anti-B7H1, Anti-CD274, Anti-PD-L1, Anti-B7-H1, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death ligand 1, Anti-Programmed cell death 1 ligand 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG65862

Properties

Application:	FC, ICC, IF, IHC (paraffin), IP
Antibody Type:	Monoclonal
Clone:	SQab1716
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant protein around aa. 19-239 (extracellular) of Human CD274 / PD-L1
MW:	33 kD
Format:	Purified