Anti-CD261 / TRAIL-R1 / DR4, clone DR-4-02 (APC)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG54240.50	50 µg		-	-	6 - 14 business days*		520.00€

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Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD... more

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Product information "Anti-CD261 / TRAIL-R1 / DR4, clone DR-4-02 (APC)"

Protein function: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. [The UniProt Consortium]

Keywords:	Anti-APO2, Anti-CD261, Anti-TRAIL-R1, Anti-TNFRSF10A, Anti-Death receptor 4, Anti-TRAIL receptor 1, Anti-TNF-related apoptosis-inducing ligand receptor 1, Anti-Tumor necrosis factor receptor superfamily member 10A
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG54240

Properties

Application:	FC, IP, ICC, IF, FA
Antibody Type:	Monoclonal
Clone:	DR-4-02
Conjugate:	APC
Host:	Mouse
Species reactivity:	human
Immunogen:	Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1