Anti-Cd204 / Msr1

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Macrophage scavenger receptor 1, also known as MSR, MSR1 and CD204, is a protein which in humans is encoded by the MSR1 gene. Enables amyloid-beta binding activity, cargo receptor activity, and low-density lipoprotein particle binding activity. Involved in several processes, including endocytosis, positive regulation of cholesterol storage, and positive regulation of macrophage derived foam cell differentiation. Acts upstream of or within lipoprotein transport. Located in plasma membrane. Is expressed in several structures, including alimentary system, limb, neural tube, reproductive system, and yolk sac. Human ortholog(s) of this gene implicated in Barrett's esophagus, arteriosclerosis, and prostate cancer. Orthologous to human MSR1 (macrophage scavenger receptor 1). Protein function: Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). [The UniProt Consortium]