Anti-CD20 (B-cell marker), clone IGEL/773

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2398SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody recognizes a protein of... more
Product information "Anti-CD20 (B-cell marker), clone IGEL/773"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody recognizes a protein of 33-37kDa, identified as CD20 (Workshop V, Code CD20.12). The antibody recognizes the extracellular domain of the protein. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, Bcell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of Bcells and its expression is restricted to normal and neoplastic Bcells, being absent from all other leukocytes and tissues. It is expressed by pre Bcells and persists during all stages of Bcell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting Bcells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in Bcell activation and cell cycle progression. Protein function: This protein may be involved in the regulation of B-cell activation and proliferation. [The UniProt Consortium]
Keywords: Anti-CD20, Anti-Bp35, Anti-MS4A1, Anti-B-lymphocyte antigen CD20, Anti-B-lymphocyte surface antigen B1, Anti-Leukocyte surface antigen Leu-16, Anti-Membrane-spanning 4-domains subfamily A member 1, CD20 Antibody (B-cell marker)
Supplier: NSJ Bioreagents
Supplier-Nr: V2398SAF

Properties

Application: FC, IF, IHC
Antibody Type: Monoclonal
Clone: IGEL/773
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human MS4A1 protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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