Anti-CD2 / CD2 molecule, clone LFA2/13325R

1 mg/ml in 1X PBS, BSA free, sodium azide free. CD2 molecule antibody recognizes CD2 molecule, a cell surface glycoprotein encoded by the CD2 gene and commonly referred to as LFA-2 or T cell surface antigen CD2. CD2 is a single-pass transmembrane protein belonging to the immunoglobulin superfamily and is primarily expressed on T lymphocytes and natural killer cells. CD2 molecule antibody is widely used in research focused on T cell activation, immune synapse formation, and lymphoid lineage identification.CD2 functions as an adhesion and co-stimulatory receptor that interacts with its ligand CD58, facilitating T cell adhesion to antigen-presenting cells. Structurally, CD2 contains extracellular immunoglobulin-like domains, a transmembrane region, and a cytoplasmic tail involved in intracellular signaling. Engagement of CD2 enhances T cell receptor signaling and promotes proliferation, cytokine production, and cytotoxic responses. CD2 localization is predominantly membranous, consistent with its role in cell-cell interaction within immune tissues.In normal tissues, CD2 expression is restricted to T cells and natural killer cells within lymphoid organs, peripheral blood, and inflamed tissues. Aberrant or clonal CD2 expression patterns are relevant in studies of T cell leukemias and lymphomas. Immunostaining typically demonstrates distinct membranous labeling in T cell populations. Clone LFA2/13325R is a recombinant rabbit monoclonal antibody generated through defined sequence expression to support consistent performance and lot-to-lot reproducibility. This CD2 molecule antibody enables investigation of T cell biology, immune activation pathways, and lymphoid neoplasms in research applications.