Anti-CD2 (T-cell Surface Antigen CD2, Erythrocyte Receptor, LFA-2, LFA-3 Receptor, Rosette Receptor,

CD2 is a 50kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion. Applications: Suitable for use in Flow Cytometry, Blocking of T Cell Activation and Partial Blocking of B Cell Costimulation. Other applications not tested. Recommended Dilution: Flow Cytometry: <0.25ug/10e5 cells in 100ul, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.