Anti-CD1a (T-cell Surface Glycoprotein CD1a, T-cell Surface Antigen T6/Leu-6, hTa1 Thymocyte Antigen

CD1a is a 49kD transmembrane glycoprotein in the CD1 family of glyco lipid presenting MHC-like molecules. CD1a contains one Ig-like domain in its extracellular region. It is expressed by most non-human mammals but not by mice or rats. Complexes of CD1a with B2-microglobulin and endogenous glycolipids are constitutively expressed on antigen-presenting cells, cortical thymocytes, and Langerhans cells. CD1a is a target of autoreactive Th22 helper T cells in the skin. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Absorption: 488nm , Emission: 565-605nm, Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.