Anti-CD19, clone SQab1869

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66321.100	100 µl		-	-	6 - 14 business days*		658.00€

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Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on... more

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Product information "Anti-CD19, clone SQab1869"

Protein function: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B- cell responses to antigens (PubMed:2463100, PubMed:1373518, PubMed:16672701). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores (PubMed:9382888, PubMed:9317126, PubMed:12387743, PubMed:16672701). Is not required for early steps during B cell differentiation in the blood marrow (PubMed:9317126). Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in response to antigen challenges (PubMed:2463100, PubMed:1373518). Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge (PubMed:9317126, PubMed:12387743, PubMed:16672701). [The UniProt Consortium]

Keywords:	Anti-CD19, Anti-B-lymphocyte antigen CD19, Anti-Differentiation antigen CD19, Anti-T-cell surface antigen Leu-12, Anti-B-lymphocyte surface antigen B4
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66321

Properties

Application:	FC, ICC, IF, IHC (paraffin), IP, WB
Antibody Type:	Monoclonal
Clone:	SQab1869
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide around the C-terminus of CD19
MW:	61 kD
Format:	Purified