Anti-CD18, clone IVA35

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG62754.100	100 µg		-	-	6 - 14 business days*		624.00€

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Protein function: Triggers neutrophil transmigration during lung injury through... more

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Product information "Anti-CD18, clone IVA35"

Protein function: Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. [The UniProt Consortium]

Keywords:	Anti-CD18, Anti-ITGB2, Anti-Integrin beta-2, Anti-Complement receptor C3 subunit beta, Anti-Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG62754

Properties

Application:	FC, IP
Antibody Type:	Monoclonal
Clone:	IVA35
Conjugate:	No
Host:	Mouse
Species reactivity:	bovine
Immunogen:	Tissue / cell preparation (Cow leucocytes)
Format:	Purified