Anti-CD163, clone 2A10/11

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG22856.100	100 µg		-	-	6 - 14 business days*		838.00€

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Protein function: Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by... more

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Product information "Anti-CD163, clone 2A10/11"

Protein function: Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium- dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. May play a role in the process of infection of porcine monocytes/macrophages by African swine fever virus (ASFV). In case of porcine reproductive and respiratory syndrome virus (PRRSV), serves mediates virion attachment and plays a role in viral entry. [The UniProt Consortium]

Keywords:	Anti-M130, Anti-CD163
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG22856

Properties

Application:	IHC (frozen), FC, ICC, IF, IP, WB
Antibody Type:	Monoclonal
Clone:	2A10/11
Conjugate:	No
Host:	Mouse
Species reactivity:	swine
Immunogen:	Porcine alveolar macrophages
Format:	Purified