Anti-CD162 / P selectin glycoprotein ligand 1 / PSGL-1, clone PSGL1/1601

Anti-CD162 / P selectin glycoprotein ligand 1 / PSGL-1, clone PSGL1/1601
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3226-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3226-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. P selectin... more
Product information "Anti-CD162 / P selectin glycoprotein ligand 1 / PSGL-1, clone PSGL1/1601"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Protein function: A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture. [The UniProt Consortium]
Keywords: Anti-CD162, Anti-PSGL-1, Anti-SELPLG, Anti-Selectin P ligand, Anti-P-selectin glycoprotein ligand 1, CD162 Antibody / P selectin glycoprotein ligand 1 / PSGL-1
Supplier: NSJ Bioreagents
Supplier-Nr: V3226-20UG

Properties

Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: PSGL1/1601
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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