Anti-CD161 (rezorstobart biosimilar) mAb, biotinylated

Anti-CD161 (rezorstobart biosimilar) mAb, biotinylated
Item number Size Datasheet Manual SDS Delivery time Quantity Price
DIM-BME100648B.50 50 µg - -

7 - 16 business days*

145.00€
DIM-BME100648B.100 100 µg - -

7 - 16 business days*

291.00€
 
Research use only. Protein function: Plays an inhibitory role on natural killer (NK) cells... more
Product information "Anti-CD161 (rezorstobart biosimilar) mAb, biotinylated"
Research use only. Protein function: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N- acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. [The UniProt Consortium]
Keywords: IMT009,IMT-009,IMT 009, Anti-CD161, Anti-KLRB1, Anti-CLEC5B, Anti-NKR-P1A, Anti-HNKR-P1a, Anti-C-type lectin domain family 5 member B, Anti-Natural killer cell surface protein P1A, Anti-Killer cell lectin-like receptor subfamily B member 1
Supplier: DIMA
Supplier-Nr: BME100648B

Properties

Antibody Type: Monoclonal
Conjugate: Biotin
Species reactivity: human
Format: Lyophilized

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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