Anti-CD14 (Monocyte and Macrophage Marker), clone LPSR/553

Anti-CD14 (Monocyte and Macrophage Marker), clone LPSR/553
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2423SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. CD14 is anchored to cells by linkage to... more
Product information "Anti-CD14 (Monocyte and Macrophage Marker), clone LPSR/553"
1 mg/ml in sterile PBS, BSA free, sodium azide free. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. Protein function: Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:8612135). [The UniProt Consortium]
Keywords: Anti-CD14, CD14 Antibody (Monocyte and Macrophage Marker)
Supplier: NSJ Bioreagents
Supplier-Nr: V2423SAF

Properties

Application: FC, IF
Antibody Type: Monoclonal
Clone: LPSR/553
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Human LPSR recombinant protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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