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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V2161SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
781.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in sterile PBS, BSA free, sodium azide free. CD11b is a cell adhesion molecule that acts... more
Product information "Anti-CD11b, clone M1/70"
1 mg/ml in sterile PBS, BSA free, sodium azide free. CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Protein function: Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. [The UniProt Consortium]
Keywords: | Anti-CD11b, Anti-ITGAM, Anti-CD11B, Anti-Integrin alpha-M, Anti-CR-3 alpha chain, Anti-Neutrophil adherence receptor, Anti-Leukocyte adhesion receptor MO1, Anti-CD11 antigen-like family member B, Anti-Cell surface glycoprotein MAC-1 subunit alpha, CD11b A |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V2161SAF |
Properties
Application: | FC, IF, FA (blocking) |
Antibody Type: | Monoclonal |
Clone: | M1/70 |
Conjugate: | No |
Host: | Rat |
Species reactivity: | human, chimpanzee, baboon, cynomolgus monkey, rhesus, rabbit, mouse |
Immunogen: | B10 mouse spleen cells enriched for T lymphocytes were used as the immunogen for this CD11b antibody. |
Format: | Purified |
Database Information
KEGG ID : | K06461 | Matching products |
UniProt ID : | P11215 | Matching products |
Gene ID : | GeneID 3684 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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