Anti-CD11b (Actived), clone CBRM1/5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG57579.100	100 µg		-	-	6 - 14 business days*		624.00€

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Protein function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of... more

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Product information "Anti-CD11b (Actived), clone CBRM1/5"

Protein function: Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. Regulates neutrophil migration (PubMed:28807980). In association with beta subunit ITGB2/CD18, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed:21193407). May regulate phagocytosis-induced apoptosis in extravasated neutrophils. May play a role in mast cell development. [The UniProt Consortium]

Keywords:	Anti-CD11b, Anti-ITGAM, Anti-CD11B, Anti-Integrin alpha-M, Anti-CR-3 alpha chain, Anti-Neutrophil adherence receptor, Anti-Leukocyte adhesion receptor MO1, Anti-CD11 antigen-like family member B, Anti-Cell surface glycoprotein MAC-1 subunit alpha
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57579