Anti-CD105 / Endoglin (RPE), clone SN6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG23526.50	50 tests		-	-	6 - 14 business days*		568.00€

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Protein function: Vascular endothelium glycoprotein that plays an important role in the... more

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Product information "Anti-CD105 / Endoglin (RPE), clone SN6"

Protein function: Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529). Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells (PubMed:17540773). Required for normal extraembryonic angiogenesis and for embryonic heart development. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors (PubMed:1692830). Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:8370410, PubMed:21737454, PubMed:22347366, PubMed:23300529). Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed:21737454, PubMed:22347366, PubMed:23300529). [The UniProt Consortium]

Keywords:	Anti-ENG, Anti-END, Anti-CD105, Anti-Endoglin
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG23526

Properties

Application:	FC
Antibody Type:	Monoclonal
Clone:	SN6
Conjugate:	No
Host:	Mouse
Species reactivity:	human, horse, rhesus monkey
Immunogen:	Partially purified cell membrane antigens from fresh leukemia cells
Format:	Purified