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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R31297 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. C-C chemokine receptor type 3, also called... more
Product information "Anti-CCR3"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. C-C chemokine receptor type 3, also called CKR3, is a protein that in humans is encoded by the CCR3 gene. The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. This receptor binds and responds to a variety of chemokines, includingeotaxin(CCL11),eotaxin-3(CCL26),MCP-3(CCL7),MCP-4(CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. Alternatively spliced transcript variants have been described. Protein function: Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064). In addition acts as a possible functional receptor for NARS1 (PubMed:30171954). [The UniProt Consortium]
Keywords: | Anti-CKR3, Anti-CCR3, Anti-CD193, Anti-CCR-3, Anti-CKR 3, Anti-CMKBR3, Anti-CC-CKR-3, Anti-C C CKR3, Anti-C-C CKR-3, Anti-Eosinophil eotaxin receptor, Anti-C-C chemokine receptor type 3, CCR3 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R31297 |
Properties
Application: | WB, IHC (paraffin), ICC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Amino acid sequence from the N-terminus of human C-C chemokine receptor type 3 (MTTSLDTVETFGTTSYYDDV) |
Format: | Purified |
Database Information
KEGG ID : | K04178 | Matching products |
UniProt ID : | P51677 | Matching products |
Gene ID | GeneID 1232 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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