Anti-CCL2 (bovine)

The Bovine CCL2 (MCP-1) polyclonal antibody is unlabeled and has been qualified for use in ELISA and Western blot applications. It is the capture antibody in the Kingfisher Biotech Bovine CCL2 ELISA. The Bovine CCL2 polyclonal antibody was produced in rabbits and is antigen-affinity purified. The reactivity by species is: (Dolphin CCL2 - Strong) (Ovine/Caprine CCL2 - Strong). For research use only. Made in the USA Protein function: Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. Plays an important role in mediating peripheral nerve injury-induced neuropathic pain. Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B. [The UniProt Consortium]