Anti-CCHa1-R

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1: 64,000 confirmed by ELISA, 3. WB positive with the immunogen protein (not applicable for synthetic peptide). Applications: ELISA, WB (positive for the recombinant immunogen protein/peptide). Buffer: Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Protein function: Receptor for the neuropeptide CCHamide-1 (PubMed:21110953, PubMed:23293632). Plays a role in the modulation of starvation-induced olfactory behavior where starved flies show increased responsiveness to food odorants, repellants and pheromones (PubMed:24067446). Contributes to regulation of sleep latency (the time required to fall asleep), amount of sleep and depth of sleep (arousability) (PubMed:30246807, PubMed:36958331). Involved in modulation of PDP1 and PDF levels in s- LNv (small ventral lateral neurons) clock neurons in response to CCHa1 released by DN1a (anterior dorsal neurons 1) clock neurons, to regulate morning activity (PubMed:30246807). In a subset of dopaminergic cells in the protocerebral anterior medial (PAM) cluster involved in suppressing arousability in response to CCHa1 secreted by gut enteroendocrine cells (PubMed:36958331). [The UniProt Consortium]