Anti-CCDC115

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA034598.25	25 µl		-		3 - 8 business days*		369.00€
ATA-HPA034598.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: Accessory component of the proton-transporting vacuolar (V)- ATPase protein... more

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Product information "Anti-CCDC115"

Protein function: Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation (PubMed:28296633). May be involved in Golgi homeostasis (PubMed:26833332). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 84%

Keywords:	Anti-Coiled-coil domain-containing protein 115
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA034598

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PREAGLRRRK GPTKTPEPES SEAPQDPLNW FGILVPHSLR QAQASFRDGL QLAADIASLQ NRIDWGRSQL RGLQEKLKQL EP (ATA-APrEST79073)