Anti-Cathepsin B

Anti-Cathepsin B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R31477 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cathepsin B is an enzymatic protein... more
Product information "Anti-Cathepsin B"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene. The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of beta-amyloid precursor protein into the amyloid plaques found in Alzheimers disease patients. However, this function is now known to be mediated by BACE1 protease. It is now thought that Cathepsin B can degrade beta-amyloid precursor protein into harmless fragments. Thus, it is conceivable cathepsin B may play a pivotal role in the natural defense against Alzheimers disease. Overexpression has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. Protein function: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. [The UniProt Consortium]
Keywords: Anti-CTSB, Anti-CPSB, EC=3.4.22.1, Cathepsin B Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R31477

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Human partial recombinant protein (AA 80-333) was used as the immunogen for this Cathepsin B antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-Cathepsin B"
Write a review
or to review a product.
Viewed