Anti-CASQ1 / Calsequestrin 1

Anti-CASQ1 / Calsequestrin 1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG43539.100 100 µl - -

6 - 14 business days*

658.00€
 
Protein function: Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein... more
Product information "Anti-CASQ1 / Calsequestrin 1"
Protein function: Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle (PubMed:28895244). Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions (PubMed:28895244). Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1, this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca(2+) entry (SOCE) activity (PubMed:27185316). {ECO:0000269, PubMed:22337878, ECO:0000269, PubMed:27185316, ECO:0000269, PubMed:28895244, ECO:0000303, PubMed:22337878}. [The UniProt Consortium]
Keywords: Anti-CASQ, Anti-CASQ1, Anti-Calsequestrin-1, Anti-Calsequestrin-1, Anti-Calmitine {ECO:0000303|PubMed:7945294}, Anti-Calsequestrin, skeletal muscle isoform, Anti-Calmitine {ECO:0000303|PubMed:7945294}, Anti-Calsequestrin, skeletal muscle isoform
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG43539

Properties

Application: FC, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide derived from human CASQ1 / Calsequestrin 1
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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