Anti-Caspase 3, clone SQab1876

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66328.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Involved in the activation cascade of caspases responsible for apoptosis... more

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Product information "Anti-Caspase 3, clone SQab1876"

Protein function: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-, -Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop- helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. [The UniProt Consortium]

Keywords:	Anti-CPP32, Anti-CASP3, EC=3.4.22.56
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66328

Properties

Application:	FC, ICC, IF, IP, WB
Antibody Type:	Monoclonal
Clone:	SQab1876
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide corresponding to aa. 1-100 of Human Caspase 3
MW:	32 kD
Format:	Purified