Anti-Caspase-11 (mouse), clone 4E11

Anti-Caspase-11 (mouse), clone 4E11
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-20T-0140-C100 100 µg -

3 - 9 business days*

358.00€
 
Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory... more
Product information "Anti-Caspase-11 (mouse), clone 4E11"
Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
Keywords: Anti-Casp4, Anti-Casp11, EC=3.4.22.64
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-20T-0140

Properties

Application: ELISA, FC, IP, WB
Antibody Type: Monoclonal
Clone: 4E11
Conjugate: No
Host: Rat
Species reactivity: mouse, rat
Immunogen: Recombinant mouse caspase-11 (p20 fragment)
Purity: >95%
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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