Anti-Calnexin, clone CANX/1541

Anti-Calnexin, clone CANX/1541
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3199SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. It recognizes a protein of 90kDa, which is... more
Product information "Anti-Calnexin, clone CANX/1541"
1 mg/ml in 1X PBS, BSA free, sodium azide free. It recognizes a protein of 90kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Protein function: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse. [The UniProt Consortium]
Keywords: Anti-p90, Anti-IP90, Anti-CANX, Anti-Calnexin, Anti-Major histocompatibility complex class I antigen-binding protein p88, Calnexin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3199SAF-100UG

Properties

Application: ELISA, ICC/IF, IHC (paraffin), WB
Antibody Type: Monoclonal
Clone: CANX/1541
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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