Anti-c-Rel Recombinant Monoclonal

c-Rel is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. Each Rel member bears a characteristic 300 amino acid N-terminal Rel homology domain (RHD). c-Rel was originally identified as the cellular version of the v-Rel oncogene derived from the avian reticuloendotheliosis retrovirus.