Anti-c-Myb Recombinant Monoclonal

c-Myb is a member of the MYB family of transcription factors. C-Myb contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. C-myb plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis [taken from NCBI Entrez Gene (Gene ID: 3093)]. Protein function: Transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. [The UniProt Consortium]