Anti-c-Myb, clone MYB286

Anti-c-Myb, clone MYB286
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3123-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3123-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The highly leukemogenic avian... more
Product information "Anti-c-Myb, clone MYB286"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. Protein function: Transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. [The UniProt Consortium]
Keywords: Anti-MYB, Anti-Proto-oncogene c-Myb, Anti-Transcriptional activator Myb
Supplier: NSJ Bioreagents
Supplier-Nr: V3123-20UG

Properties

Application: FC, IF
Antibody Type: Monoclonal
Clone: MYB286
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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