Anti-BTLA

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-486.50	50 µl		-	-	Request delivery time estimate		232.00€
ABS-KC-486.100	100 µl		-	-	Request delivery time estimate		332.00€

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Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor... more

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Product information "Anti-BTLA"

Protein function: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044). [The UniProt Consortium]

Keywords:	Anti-B- and T-lymphocyte attenuator, Anti-B- and T-lymphocyte-associated protein, Anti-CD antigen CD272, BTLA Antibody
Supplier:	Absea
Supplier-Nr:	KC-486

Properties

Antibody Type:	Monoclonal
Clone:	3D7
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human BTLA
Format:	Solution

Database Information

KEGG ID :	K06707 \| Matching products
UniProt ID :	Q7Z6A9 \| Matching products
Gene ID :	GeneID 151888 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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