Anti-BSEP Monoclonal

Anti-BSEP Monoclonal
NEW
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A501-019-T 20 µl -

2 - 8 business days*

172.00€
A501-019 100 µl -

2 - 8 business days*

652.00€
 
Protein Function: Catalyzes the transport of the major hydrophobic bile salts, such as taurine... more
Product information "Anti-BSEP Monoclonal"
Protein Function: Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner (PubMed:15791618, PubMed:16332456, PubMed:18985798, PubMed:19228692, PubMed:20010382, PubMed:20398791, PubMed:22262466, PubMed:24711118, PubMed:29507376, PubMed:32203132). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (PubMed:16332456). Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion (PubMed:15901796, PubMed:18245269) [The Uniprot Consortium]
Keywords: Anti-ABCB11, Anti-Bile salt export pump, Anti-ATP-binding cassette sub-family B member 11
Supplier: Bethyl Laboratories
Supplier-Nr: A501-019

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: BLGM019
Conjugate: No
Host: Mouse
Species reactivity: human
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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