Anti-BRMS1 [R95-6M-2] Monoclonal Antibody

BRMS1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma [The Uniprot Consortium]