Anti-BRMS1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59399.100	100 µl		-	-	10 - 15 business days*		707.00€

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Protein function: Transcriptional repressor. Down-regulates transcription activation by... more

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Product information "Anti-BRMS1"

Protein function: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down- regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. [The UniProt Consortium]

Keywords:	Anti-BRMS1, Anti-Breast cancer metastasis-suppressor 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59399

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse
Immunogen:	Recombinant fusion protein corresponding to aa. 90-210 of Human BRMS1 (NP_056214.1)
MW:	28 kD
Format:	Affinity Purified