Anti-BRD7

Anti-BRD7
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-304A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-304A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-304A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Acts both as coactivator and as corepressor. May play a role in chromatin... more
Product information "Anti-BRD7"
Protein function: Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR. Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase. [The UniProt Consortium]
Keywords: Anti-BRD7, Anti-BP75, Anti-Protein CELTIX-1, Anti-75 kDa bromodomain protein, Anti-Bromodomain-containing protein 7
Supplier: Bethyl Laboratories
Supplier-Nr: A302-304A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A302-304A-T maps to a region between residue 601 and 651 of human bromodomain containing 7 using the numbering given in entry NP_037395.2 (GeneID 29117).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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