Anti-Bone Morphogenetic Protein 11 (BMP11, Growth/differentiatiion factor 11, GDF11)

Bone Morphogenetic Protein 11 (GDF-11) is a secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. It plays critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. It exists as a disulfide-linked homodimer. It belongs to the TGF-beta family. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: Formalin fixed paraffin embedded., Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.