Anti-Bnip3L

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG54385.50	50 µg		-	-	6 - 14 business days*		520.00€

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Protein function: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins.... more

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Product information "Anti-Bnip3L"

Protein function: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor. [The UniProt Consortium]

Keywords:	Anti-NIP3L, Anti-BNIP3A, Anti-BNIP3L, Anti-NIP3-like protein X, Anti-Adenovirus E1B19K-binding protein B5, Anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, Anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG54385

Properties

Application:	WB, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Peptide corresponding to aa 77-92 of human Bnip3L (accession no. AF067396) This amino acid sequence is identical to that of mouse
Format:	Affinity Purified