Anti-BNIP3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA003015.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA003015.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role... more

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Product information "Anti-BNIP3"

Protein function: Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 89% and to rat: 89%

Keywords:	Anti-NIP3, Anti-BNIP3, Anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA003015

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MSQNGAPGMQ EESLQGSWVE LHFSNNGNGG SVPASVSIYN GDMEKILLDA QHESGRSSSK SSHCDSPPRS QTPQDTNRAS ETDTHSIGEK NSSQSEEDDI ERRKEVESIL KKNSDWIWDW SSRPENIPPK EFLFKHPKRT ATLSMRNTSV MKKG (ATA-APrEST70388)