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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG44042.100 | 100 µl | - | - |
10 - 15 business days* |
707.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Induces apoptosis. Interacts with viral and cellular anti- apoptosis proteins.... more
Product information "Anti-Bnip 3L"
Protein function: Induces apoptosis. Interacts with viral and cellular anti- apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor. {ECO:0000269, PubMed:10381623, ECO:0000269, PubMed:21264228}. [The UniProt Consortium]
| Keywords: | Anti-NIP3L, Anti-NIP3L, Anti-BNIP3L, Anti-BNIP3A, Anti-NIP3-like protein X, Anti-NIP3-like protein X, Anti-Adenovirus E1B19K-binding protein B5, Anti-Adenovirus E1B19K-binding protein B5, Anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, Ant |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG44042 |
Properties
| Application: | ICC, IF, IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 95-180 of human BNIP3L (NP_004322.1) |
| MW: | 24 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K15465 | Matching products |
| UniProt ID : | O60238 | Matching products |
| Gene ID : | GeneID 665 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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