Anti-BIRC6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA074738.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA074738.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Anti-apoptotic protein which can regulate cell death by controlling caspases... more

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Product information "Anti-BIRC6"

Protein function: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 99%

Keywords:	Anti-BIRC6, Anti-BRUCE, Anti-APOLLON, Anti-KIAA1289, Anti-RING-type E3 ubiquitin transferase BIRC6, Anti-Baculoviral IAP repeat-containing protein 6, Anti-Ubiquitin-conjugating BIR domain enzyme apollon
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA074738

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GSTDNESCTN SELNSPLVRR TLPVLLLYSI KESDEKAGKI FSQMNNIMSK SLHDDGFTVP QIIEMELDSQ EQLLLQDPPV TYIQQFADAA (ATA-APrEST93245)