Anti-BICDL1

Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): 97%. Homologies: Highest antigen sequence identity to the following orthologs: Mouse - 97%, Pig - 98%, Cynomolgus monkey - 99%. IHC Verification: succeed. WB Verification: -. IP Verification: -. IF Verification: -. FC Verification: -. IP-MS Verification: -. Cross reactivity: Not tested. Sandwich ELISA Verification: -. Antigen ID: ABS-PP-8550. Core Sequence: YEQMHKELTD KLEHLEQEKH ELRRRFENRE GEWEGRVSEL ESDVKQLQDE LERQQIHLRE ADREKSRAVQ ELSEQNQRLL DQLSRASEVE RQLSMQVHAL REDFREKNSS TNQHIIRLES LQAEIKMLSD. Recombinant Antibody: Protein Function: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Predominantly recruits 2 dyneins, which increases both the force and speed of the microtubule motor. Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis [The Uniprot Consortium]