Anti-BICD2

Anti-BICD2
Promotion:

Bethyl is giving away a free permanent marker for every Bethyl purchase until supplies last!

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-319A-T 10 µl (10 µg) -

3 - 9 business days

125.00€
A303-319A 100 µl (100 µg) -

3 - 9 business days

430.00€
 
Protein function: Acts as an adapter protein linking the dynein motor complex to various cargos... more
Product information "Anti-BICD2"
Protein function: Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non- processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis. [The UniProt Consortium]
Keywords: Anti-BICD2, Anti-Bic-D 2, Anti-KIAA0699, Anti-Protein bicaudal D homolog 2
Supplier: Bethyl Laboratories
Supplier-Nr: A303-319A-T

Properties

Application: IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse)
Immunogen: synthetic peptide. The epitope recognized by A303-319A-T maps to a region between residue 625 and 675 of human Bicaudal D Homolog 2 using the numbering given in entry NP_056065.1 (GeneID 23299).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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