Anti-Beclin 1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-566A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A302-566A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Plays a central role in autophagy (PubMed:23184933). Acts as core subunit of... more

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Product information "Anti-Beclin 1"

Protein function: Plays a central role in autophagy (PubMed:23184933). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate, different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3- C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense. [The UniProt Consortium]

Keywords:	Anti-BECN1, Anti-GT197
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-566A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A302-566A-T maps to a region between residue 1 and 50 of human Beclin 1 using the numbering given in entry NP_003757.1 (GeneID 8678).
Format:	Antigen Affinity Purified