Anti-BCL2L2 (Bcl-w, Bcl-2-like Protein 2, Bcl2-L-2, Apoptosis Regulator Bcl-W, BCLW, KIAA0271

Bcl-w is a pro-survival (apoptotic) member of the Bcl-2 family, a family involved in the regulation of cellular apoptosis at the mitochondrion. Relative to its Bcl-2 counterparts there is considerably less data on this prticular protein. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Applications: Suitable for use in Neutralization. Other applications not tested. Recommended Dilution: Neutralization: 10ug to neutralize 1ug, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.