Anti-BBS9

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA021289.25	25 µl		-		3 - 8 business days*		246.00€
ATA-HPA021289.100	100 µl		-		3 - 8 business days*		491.00€

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Protein function: The BBSome complex is thought to function as a coat complex required for... more

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Product information "Anti-BBS9"

Protein function: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 85% and to rat: 85%

Keywords:	Anti-BBS9, Anti-PTHB1, Anti-Protein PTHB1, Anti-Bardet-Biedl syndrome 9 protein, Anti-Parathyroid hormone-responsive B1 gene protein
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA021289

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: QEDTQELGWE ETVDAAISHL LKTCLSKSSK EQALNLNSQL NIPKDTSQLK KHITLLCDRL SKGGRLCLST DAAAPQTMVM PGGCTTIPES DLEERSVEQD STELFTNHRH LTAETPRPEV SPLQ (ATA-APrEST74942)