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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form... more
Product information "Anti-BAK1"
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. Protein function: Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases. [The UniProt Consortium]
Keywords: | Anti-BAK, Anti-BAK1, Anti-Bcl2-L-7, Anti-Bcl-2-like protein 7, Anti-Apoptosis regulator BAK, Anti-Bcl-2 homologous antagonist/killer, BAK1 Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-60009 |
Properties
Application: | WB, IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | A synthetic peptide of human BAK1 |
Database Information
KEGG ID : | K14021 | Matching products |
UniProt ID : | Q16611 | Matching products |
Gene ID | GeneID 578 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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