Anti-BAG1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA018121.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA018121.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a... more

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Product information "Anti-BAG1"

Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:27474739, PubMed:9873016, PubMed:24318877). Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity (PubMed:12724406). Markedly increases the anti-cell death function of BCL2 induced by various stimuli (PubMed:9305631). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 84% and to rat: 83%

Keywords:	Anti-HAP, Anti-BAG1, Anti-BAG-1, Anti-Bcl-2-associated athanogene 1, Anti-BAG family molecular chaperone regulator 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA018121

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GKSLKEMETP LSALGIQDGC RVMLIGKKNS PQEEVELKKL KHLEKSVEKI ADQLEELNKE LTGIQQGFLP KDLQAEALCK LDRRVKATIE QFMKILEEID TLILPENFKD SRLKRKGLVK KVQAFLAECD TVEQNICQET E (ATA-APrEST72797)