Anti-Bag1

Anti-Bag1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45129.50 50 µg - -

10 - 15 business days*

501.00€
 
Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a... more
Product information "Anti-Bag1"
Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:27474739, PubMed:9873016, PubMed:24318877). Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity (PubMed:12724406). Markedly increases the anti-cell death function of BCL2 induced by various stimuli (PubMed:9305631). [The UniProt Consortium]
Keywords: Anti-HAP, Anti-BAG1, Anti-BAG-1, Anti-BAG-1, Anti-Bcl-2-associated athanogene 1, Anti-Bcl-2-associated athanogene 1, Anti-BAG family molecular chaperone regulator 1, Anti-BAG family molecular chaperone regulator 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45129

Properties

Application: IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthetic peptide corresponding to C-terminal region of human BAG1
MW: 39 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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