Anti-BAG-1, clone RM356

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R20378-0.1ML 100 µl - -

3 - 10 business days*

772.00€
 
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to total... more
Product information "Anti-BAG-1, clone RM356"
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to total human BAG-1 protein, including long (BAG-1L), medium (BAG-1M) and short (BAG-1S) isoforms. Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:27474739, PubMed:9873016, PubMed:24318877). Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity (PubMed:12724406). Markedly increases the anti-cell death function of BCL2 induced by various stimuli (PubMed:9305631). [The UniProt Consortium]
Keywords: Anti-HAP, Anti-BAG1, Anti-BAG-1, Anti-Bcl-2-associated athanogene 1, Anti-BAG family molecular chaperone regulator 1, BAG-1 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R20378

Properties

Application: WB, IHC (paraffin)
Antibody Type: Monoclonal
Clone: RM356
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: peptide corresponding to human BAG-1 (Bcl-2-associated athanogene 1)
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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