Anti-BAFF / BLyS, clone C257/1638

Anti-BAFF / BLyS, clone C257/1638
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3216SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. BAFF/BLyS/CD257 is a type II transmembrane... more
Product information "Anti-BAFF / BLyS, clone C257/1638"
1 mg/ml in sterile PBS, BSA free, sodium azide free. BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3). Protein function: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. [The UniProt Consortium]
Keywords: Anti-BAFF, Anti-TNFSF13B, BAFF Antibody / BLyS
Supplier: NSJ Bioreagents
Supplier-Nr: V3216SAF-100UG

Properties

Application: FC, IF
Antibody Type: Monoclonal
Clone: C257/1638
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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