Anti-BACE1 [R03-9C8] Monoclonal Antibody

BACE1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Responsible for the proteolytic processing of the amyloid precursor protein (APP) (PubMed:29325091). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed:29325091). Cleaves CHL1 (PubMed:29325091) [The Uniprot Consortium]